Validated molecular diagnostic

Detect Aspergillus before it costs you a batch.

A duplex TaqMan qPCR assay built for cannabis cultivators. Proactive, science-backed Aspergillus screening that catches contamination at cultivation — not at compliance testing.
A graph displaying a quantitative PCR run for DNA amplification, showing a curve indicating fluorescence against the number of cycles. An inset image of virus-like particles is positioned to the right, with text indicating overall accuracy and detection details.
The gap in compliance testing

Compliance testing catches failures. We catch problems early.

Airborne spores spread silently.

Aspergillus conidia disperse through air and dust across cultivation, harvest, drying, trimming, and storage — often invisibly until it’s too late.

End-of-pipeline detection leaves no
options.

When contamination is found at state compliance testing, remediation is often impossible — and product disposal is the only path.

Early screening changes the outcome.

Our assay integrates into your workflow as an environmental and tissue monitor — identifying pressure before it escalates into batch loss.

Validated molecular diagnostic

What is Aspergillus?

A simple swab-based workflow designed to fit into cultivation and post-harvest operations without disrupting your team.
A. fumigatus
Primary pathogen
Leading cause of invasive aspergillosis; airborne conidia are a primary inhalation hazard.
A. niger
mycotoxin risk
Common post-harvest contaminant; associated with ochratoxin.
A. flavus / A. parasiticus
mycotoxin risk
Major aflatoxin producers; potent carcinogens regulated across food and cannabis industries.
A. terreus
Antifungal Resistant
Resistant to amphotericin B; increasingly significant in immunocompromised patients.
Method

From swab to answer.

A simple swab-based workflow designed to fit into cultivation and post-harvest operations without disrupting your team.
01
Swab collection
Swab cannabis flower, plant tissue, surfaces, or environmental sites like drying rooms, trim areas, and HVAC zones.
02
Fungal lysis & extraction
Proprietary extraction ensures efficient fungal cell lysis. An internal control confirms sample integrity in every run.
03
Duplex TaqMan qPCR
Primer-probe sets simultaneously target only the regulated species of Aspergillus, and nothing else.
04
Quantitative result reporting
Results include a fungal load estimate and live/dead determination to enable targeted remediation before product advances to compliance testing.
Technical validation

Inclusivity and Exclusivity Analysis

Every performance claim is backed by rigorous in-lab validation — limit of detection studies, 30-replicate species-specific studies, and blinded operator accuracy trials.
OVERALL ACCURACY
99.2%
Accuracy vs. Culture Plating
120 samples (90 positive, 30 negative) tested by a blinded, independent operator. Compared head-to-head against colony-forming unit confirmation via plating.
Low input (~3 CFU) 96.7%
Mid input (~25 CFU) 100%
High input (~100 CFU) 100%
False positives detected (In a 30 sample study size) Not detected
LIMIT OF DETECTION
7.6 cells/rxn
Sensitivity across all four species
Determined across serial dilutions from 500,000 down to 2 copies per reaction (10 replicates each), then confirmed with 30 replicates at near-LoD concentrations per species.
A. niger LoD 15 copies (97%)
A. flavus LoD 7 copies (100%)
A. fumigatus LoD 7 copies (97%)
A. terreus LoD 15 copies (97%)
FIELD READINESS
48hr
Sample stability at ambient temperature
Accuracy validation samples were incubated at room temperature for 48 hours before testing — mirroring standard shipping times from customer facilities to the TUMI Genomics laboratory.
A laboratory technician wearing blue gloves is holding a small clear tube labeled with a plus sign, as a dropper releases a liquid into it. The background shows a blurred laboratory setting.
Method

From swab to answer.

Cross-reactivity was evaluated via in silico BLAST analysis against 253 microorganisms commonly associated with Cannabis sativa, Humulus lupulus (hops), and the wider cultivation environment.
Only two organisms exceeded the 80% similarity threshold for concern — and neither represents a meaningful risk to cannabis safety testing.

A. oryzae —
an industrial fermentation species, not found in grow facilities.

A. parasiticus — closely related to A. flavus; detection here is clinically meaningful, not a false positive.

A horizontal bar chart displaying the similarity scores of various organisms. A. fumigatus shows a score of 100%, followed by A. oryzae at 98.6%. Other organisms like Trichoderma harzianum and Fusarium oxysporum have lower scores, with a threshold for concern indicated at 80%.
Inclusivity analysis

99.3%

of 1,524 known sequence variants showed 100% homology to primer/probe sequences. 100% of variants showed greater than 95% homology.
A. niger
213
sequences analyzed — 100% match
A. flavus
513
sequences analyzed — 98.8% at 100%
A. fumigatus
622
sequences analyzed — 99.7% at 100%
A. terreus
176
sequences analyzed — 99.4% at 100%
Primers and probes target highly conserved genomic regions. No analyzed variant contained more than a single SNP within any individual primer or probe.
Method

Built by scientists who've done it before.

Our lead scientists bring deep molecular biology expertise — decades designing and validating in vitro assays, with specific depth in cannabis pathogen diagnostics and remediation.
A woman with long, straight brown hair wearing a gray and white striped blazer over a black shirt. She is standing in front of a black vertical slatted background.
Tassa Saldi, PhD
Lead Scientist & CSO
Publications on PubMed ↗
A man with short, curly dark hair and a beard stands against a textured black background. He is wearing a dark fleece jacket over a green shirt. The image is well-lit, highlighting the subject's features.
Alfonso Garrido-Lecca, PhD
Lead Scientist & Head of R&D
Publications on PubMed ↗

Stop finding out at the compliance stage.

Integrate proactive Aspergillus screening into cultivation, drying, and post- harvest — and protect your harvest before it ever reaches state testing.